Juvenile idiopathic arthritis associated with autoimmune thyroid disorders and autoimmune cholangitis
نویسندگان
چکیده
منابع مشابه
The frequency of autoimmune thyroid disorders in juvenile idiopathic arthritis.
Few studies have been performed to investigate autoimmune diseases associated with organ non-specific rheumatological disorders in children, such as juvenile idiopathic arthritis (IA). The objective in this study was to determine the frequency of autoimmune diseases of the thyroid gland in children with JIA. Eighty patients with JIA and 81 healthy sex- and age-matched controls were enrolled in ...
متن کاملThe autoimmune burden in juvenile idiopathic arthritis
BACKGROUND Juvenile idiopathic arthritis (JIA) is a chronic inflammatory arthritis of unknown origin which can be considered an autoimmune disease (AD). The aim of this study is to analyse the presence of two or more autoimmune diseases (polyautoimmunity) in patients suffering from JIA and to evaluate the occurrence of ADs in their families. METHODS Seventy-nine patients diagnosed with JIA ag...
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Secondary thrombotic microangiopathies are associated with several underlying conditions, with most of them being resolved after the treatment of background disease. Thrombotic thrombocytopenic purpura (TTP) is a rare microangiopathy presenting with anemia, thrombocytopenia, and neurological deficits, occurring most often in various autoimmune diseases due to inhibition of ADAMTS13 by autoantib...
متن کاملThyroid function, autoimmune thyroiditis and coeliac disease in juvenile idiopathic arthritis.
OBJECTIVES Autoimmune diseases have been associated with some organ non-specific rheumatological disorders such as rheumatoid arthritis and systemic lupus erythematosus; however, few studies have been performed in an extensive cohort of children with juvenile idiopathic arthritis (JIA). Our objective was to evaluate the thyroid function and the prevalence of antithyroid antibodies, autoimmune t...
متن کاملAutoimmune response to transthyretin in juvenile idiopathic arthritis.
Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatological condition. Although it has been proposed that JIA has an autoimmune component, the autoantigens are still unknown. Using biochemical and proteomic approaches, we identified the molecular chaperone transthyretin (TTR) as an antigenic target for B and T cell immune responses. TTR was eluted from IgG complexes and aff...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2001
ISSN: 1460-2172
DOI: 10.1093/rheumatology/40.8.942